New Delhi, Sep 11 : The dramatic changes in the early years of life in adolescents and young adults with regards to diet and lifestyle, obesity, microbiome and environment have resulted in an “genuine rise” in the incidence of early-onset forms of various cancers across the globe according to a new Nature research warns.In the last several decades, there has been an increase in the number of cancers that are early-onset, typically described as cancers detected in adults younger than 50 of age in the breast, the oesophagus, colorectum, endometrium the extrahepatic bile passageway, gallbladders, head and neck kidney liver, bone marrow, liver pancreas, prostate thyroid and stomach has increased in several countries.
Evidence suggests that there is an aetiological component of risk factors in early life and early adulthood.” was the conclusion of the worldwide study that was published in the journal Nature Reviews Clinical Oncology, and led by researchers from Harvard T.H.Chan School of Public Health, Boston.
In the last 20 years, significant multigenerational shifts in the exposome have taken place (including shifts in diet habits, obesity, the environment and the microbiome which all of which may interact with genetic or genomic susceptibilities).
The prevalence of cancers of different organs discovered in people younger than 50 of old has been increasing in various parts of the world since the 1990s.
“The early-onset cancer epidemic could be a sign of rising patterns in the progression of various chronic illnesses in the future and young generations,” the researchers wrote.
They stressed that increasing consciousness of the cancer outbreak that begins in early stages as well as improving the early-life setting should be the first priority for us.
“These could decrease the impact of both late-onset and early-onset cancers.” they said.
To investigate early-life exposures as well as their consequences for various cancers, future cohort studies with dedicated bio-banking as well as data collection technology The study noted.
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