Beijing 19th August : Consuming a large amount of Green Vegetables in conjunction with the dietary supplement chlorophyllin can help ease IBD (IBD) that includes ulcerative colitis and Crohn’s disease according to research.Additionally, chlorophyllinthe compound that is derived from the Green pigment that is found in plants significantly reduces mortality associated with IBD diarrhoea, weight loss, diarrhoea and the hidden blood in the stool intestinal epithelial injury and infiltration of inflammation-related cells, said researchers from the Center for Diabetes and Metabolism Research at Sichuan University in China and from Cedars Sinai Medical Center in Los Angeles.
The researchers believed the findings could provide a path to a less invasive treatment of IBD.
“Consuming green-colored Vegetables or pigments such as chlorophyllin could help people with an Inflammatory Bowel disorder,” said Xiaofeng Zheng, Ph.D., of Sichuan University and a co-author of the study.
IBD has resulted in a global health burden due to the burden of the increasing price of treating the disease.Although the specific reason of IBD isn’t understood fully the contributing factors are stress and lifestyle, environmental and dietary choices that include a large consumption of fish or meat.
Chronic inflammation and a defect in autophagy, the body’s way of eliminating damaged cells to make way for healthier, newer cells — as well as lysosomal strain (an irregularity in an organelle that leads to inflammation) are also associated with the condition.
Current treatments for IBD comprise treatments that suppress the immune system (immunosuppressants) and surgeries.
However long-term usage of immunosuppressive treatments can result in serious adverse effects that include opportunistic infections and even organ failure.
In the study, published in the American Journal of Physiology-Gastrointestinal and Liver Physiology, researchers found taking an oral chlorophyllin supplement reduced colitis and abnormalities in the intestinal epithelia of mice.
Additionally, the consumption of chlorophyllin and Green Vegetables could be beneficial for IBD recuperation, in part through alleviation of inflammation and autolysosomal flux (a process that utilizes lysosomes to break down and eliminate toxic organelles and molecules).
Green pigments that is found in these food items and supplements may trigger an eating signalling that can regulate autophagy in the cells, which can reduce IBD symptoms.