New York, Aug 19 : Metformin is a frequently prescribed diabetic medication may help lower the chance of hospitalizations, emergency room visits or even death due to Covid-19 by 50 percent when prescribed at an early point in the onset of symptoms, according to an investigation. “Our study suggests that metformin may decrease the chance of having to visit an emergency room or being admitted to hospital to treat Covid-19” stated Carolyn Bramante Associate Professor of paediatrics and internal medicine at the University of Minnesota Medical School.
The study looked into whether metformin, fluvoxamine at low doses, an antidepressant; and Ivermectin an antiparasitic or any combination of them could serve as potential treatments to avoid ER visits or hospitalization, and long-term Covid in 1,323 participants, including pregnant women.
The study, published in the New England Journal of Medicine did not show any positive effects on the treatment with either ivermectin or low dose fluvoxamine.
The study also included people who were vaccinated as well as those who weren’t.
“Although we know that Covid-19 vaccines are extremely efficient, we are aware that fresh variants of the virus could elude immunity and vaccines might not be accessible worldwide.
Therefore, we decided to investigate safe, affordable and affordable alternatives for treatment in outpatients as quickly as we can,” said Bramante.
“Understanding whether treatments that are not inpatient could help more people to are able to survive the disease if they develop it and suffer lesser long-term effects is a crucial part of the pandemic response.
“Observational research and in vitro tests are not conclusive, but they can provide bodies of evidence” Bramante noted.