Varanasi, UP, Nov 30 : .Researchers from the Molecular Biology Unit of the Institute of Medical Sciences at Banaras Hindu University, (IMS-BHU), have conducted a study that highlighted the role of small RNAs during Chandipura virus infections.
This can be used for microRNA-based therapy. Neha Pandey, a well-known virologist who is also the head of the Molecular Biology Unit, conducted research on the pathogenesis Chandipura virus.
The study was published in the peer-reviewed international scientific journal “Journal of Biomedical Science”.
Covid-19 management has shown that RNA-based vaccines and drugs may be an important tool in the prevention of infectious disease.
“Whatever is left unattended today could be a threat tomorrow.” Singh stated that it is important to understand the complex mechanism of neglected viruses.
He stated that the Chandipura virus was discovered in 1966 during an unknown fever epidemic in Chandipur village, Nagpur, Maharashtra.
Between 2002 and 2004, the Chandipura virus attracted particular attention from virologists when it was first reported in Andhra Pradesh and Maharashtra.
He stated that there are no antiviral drugs to treat the Chandipura virus.To prevent the spread of the virus by vectors, it is important to maintain good nutrition, hygiene, and awareness in rural areas.
Brain infections are quickly responded to by the microglial cells.Inducing inflammation and over-activating microglial cells by Chandipura virus infection in brain,
He stated that the research revealed a mechanism that could be responsible for the encephalitis-like symptoms that can occur with Chandipura virus infection.
The Chandipura virus (RNA virus) is a Chandipura virus.
Children under 15 years old are more susceptible to Chandipura virus infection, and have a higher rate of mortality.
Infected mosquitoes and sandflies spread the Chandipura virus.According to some reports, the main vector for Chandipura virus transmission is the sandflies of Phlebotomus and Sergentomyia species.
Infections in the brain can cause inflammation and disrupt the brain’s normal functioning.Infection with Chandipura virus can cause high fever, vomiting, convulsions and other brain disorders similar to encephalitis.
Patients who are severely affected may fall into a coma and other serious complications.
These symptoms fall under the Acute Encephalitis Syndrome (AES) category.
A majority of AES cases are thought to be caused either by bacterial meningitis (BMV) or Japanese encephalitis virus infection (JEV).In more than half of cases of AES, however, the source or factor of the disease is not known.
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